The glossopharyngeal nerve (IX cranial nerve pair): anatomical considerations and neuralgia: literature review / O nervo glossofaringeo (IX par de nervo craniano): considerações anatômicas e neuralgia: revisão da literatura

The glossopharyngeal nerve (IX cranial nerve) is a mixed nerve, with both motor and sensory function. This relates to the tongue and pharynx. Glossopharyngeal neuralgia is a rare nervous neuropathy, with poristic, lancinating and paritary crises, usually unilateral. The aim of the study was to review the literature on glossopharyngeal neuralgia of the nerve (IX cranial nerve), highlighting the anatomical aspects of this nerve and the possible causes and complications of neuralgia as well as forms of treatment. A literature review was carried out in the international Pubmed database. The literature review included 72 articles from 2015 to 2021. The keywords used were: "anatomy of glossopharyngeal neuralgia". Of the 72 articles, 7 were used for this literature review. Uncommon as nervous/glossophingeal etiologies and pathologies are neurological abnormalities/neurovarises and pathologies are neurovascular/neurovariseal lesions. Pharmacological treatment approaches mentioned in the literature were therapy with antiepileptics and antidepressants such as carbamazepine and gabapentin; a microvascular decompression; and gamma knife radiosurgery(AU)

O nervo glossofaríngeo (IX par de nervo craniano) é um nervo misto, contendo função tanto motora como sensitiva. Este nervo relaciona-se com a língua e com a faringe. A neuralgia do nervo glossofaríngeo é uma neurapatia rara, sendo caracterizada por crises dolorosas, lancinantes e paroxísticas, geralmente unilaterais. O objetivo do estudo foi realizar uma revisão de literatura sobre a neuralgia do nervo glossofaríngeo (IX par de nervo craniano), destacando os aspectos anatômicos deste nervo e as possíveis causas e complicações da neuralgia bem como formas de tratamento. Foi realizada uma revisão da literatura na base de dados internacional Pubmed. A revisão da literatura incluiu 72 artigos no período de 2015 a 2021. As palavras-chave utilizadas foram: "anatomia da neuralgia do glossofaríngeo". Dos 72 artigos, 7 foram utilizados para esta revisão de literatura. Verificouse que a neuralgia do nervo glossofaríngeo é incomum e as etiologias mais encontradas foram compressão neurovascular/variações vasculares, patologias e traumas. As abordagens dos tratamentos mencionadas na literatura foram a terapia farmacológica da área com antiepilépticos e antidepressivos, como carbamazepina e gabapentina; a descompressão microvascular; e radiocirurgia com faca gama(AU)

Mastoid and opisthion-bimastoid triangles for sex determination in a Brazilian sample / Triangulos mastoideo y opistión-bimastoideo para la determinación del sexo en una muestra brasileña

SUMMARY: Human identification involving mutilation, advanced decomposition, and skeletonized materials is a challenge for professionals in forensic medicine and dentistry. This study was aimed at a morphometric analysis of the mastoid and bimastoid triangles to determine sex in a Brazilian population. The sample included 80 human skulls (34 females and 46 males; age: 18 to 60 years) from individuals with death certificates. Linear measurements (mm) of the mastoid process - right (n=3) and left (n=3) - and the opisthion- bimastoid (n=3) triangles were taken (digital caliper) by two previously trained researchers. Three cranial points - asterion, porion and process - were determined for the right and left mastoid triangle and three others - (1) opisthion and (2) right and (3) left mastoid - for the bimastoid triangle. Heron's formula was used to calculate the area of the triangles assessed. Data were submitted to the Shapiro- Wilk normality test, followed by the unpaired Student's t test or the Mann-Whitney U test, depending on the data distribution verified in the normality test (GraphPad Prism 5.01; p<0.05). The ROC curve was used to measure the accuracy of the variables toward sex determination. The opisthion-bimastoid triangle showed high accuracy and significant differences in all the variables assessed and thus was considered a potential element for sex determination in the Brazilian population assessed.

RESUMEN: La identificación humana que comprende la mutilación, descomposición avanzada y materiales esqueletizados, es un desafío para los profesionales de la medicina forense y de la odontología. Este estudio tuvo como objetivo un análisis morfométrico de los triángulos mastoideo y bimastoideo para determinar el sexo en una población brasileña. La muestra incluyó 80 cráneos humanos (34 mujeres y 46 hombres; edad: 18 a 60 años) de sujetos con certificado de defunción. Se tomaron las medidas lineales (mm) del proceso mastoides - derecha (n = 3) e izquierda (n = 3) - y los triángulos opistion-bimastoide (n = 3) (caliper digital) por dos investigadores previamente entrenados. Se determinaron tres puntos craneales - asterion, porion y proceso mastoides - para el triángulo mastoideo derecho e izquierdo y otros tres - (1) opistion y (2) proceso mastoides derecho e izquierdo - para el triángulo bimastoideo. Se utilizó la fórmula de Heron para calcular el área de los triángulos evaluados. Los datos se analizaron con la prueba de normalidad de Shapiro-Wilk, seguida de la prueba t de Student para datos no apareados o la prueba U de Mann-Whitney, según la distribución de datos verificada en la prueba de normalidad (GraphPad Prism 5.01; p <0.05). La curva ROC se utilizó para medir la precisión de las variables hacia la determinación del sexo. El triángulo opistion-bimastoide mostró una alta precisión y diferencias significativas en todas las variables evaluadas, por lo que se consideró un elemento probable para la determinación del sexo en la población brasileña evaluada.

A SERM increasing the expression of the osteoblastogenesis and mineralization-related proteins and improving quality of bone tissue in an experimental model of osteoporosis

Abstract Raloxifene is an antiresorptive drug, selective estrogen receptor modulator (SERM) used in the treatment of osteoporosis. Objective To evaluate proteins related to bone repair at the peri-implant bone in a rat model of osteoporosis treated with raloxifene. Material and Methods 72 rats were divided into three groups: SHAM (healthy animals), OVX (ovariectomized animals), and RLX (ovariectomized animals treated with raloxifene). Raloxifene was administered by gavage (1 mg/kg/day). Tibial implantation was performed 30 days after ovariectomy, and animals were euthanized at 14, 42, and 60 days postoperatively. Samples were collected and analyzed by immunohistochemical reactions, molecular analysis, and microtomographic parameters. Results RLX showed intense staining of all investigated proteins at both time points except for RUNX2. These results were similar to SHAM and opposite to OVX, showing mild staining. The PCR gene expression of OC and ALP values for RLX (P<0.05) followed by SHAM and OVX groups. For BSP data, the highest expression was observed in the RLX groups and the lowest expression was observed in the OVX groups (P<0.05). For RUNX2 data, RLX and SHAM groups showed greater values compared to OVX (P<0.05). At 60 days postoperatively, microtomography parameters, related to closed porosity, showed higher values for (Po.N), (Po.V), and (Po) in RLX and SHAM groups, whereas OVX groups showed lower results (P<0.05); (BV) values (P=0.009); regarding total porosity (Po.tot), RLX group had statistically significant lower values than OVX and SHAM groups (P=0.009). Regarding the open porosity (Po.V and Po), the SHAM group presented the highest values, followed by OVX and RLX groups (P<0.05). The Structural Model Index (SMI), RLX group showed a value closer to zero than SHAM group (P<0.05). Conclusions Raloxifene had a positive effect on the expression of osteoblastogenesis/mineralization-related proteins and on micro-CT parameters related to peri-implant bone healing.

Alveolar bone healing in rats: micro-CT, immunohistochemical and molecular analysis

Abstract Alveolar bone healing after upper incisor extraction in rats is a classical model of preclinical studies. The underlying morphometric, cellular and molecular mechanism, however, remains imprecise in a unique study. Objectives The aim of this study was therefore to characterize the alveolar bone healing after upper incisor extraction in rats by micro computed tomographic (Micro-CT), immunohistochemical and real-time polymerase chain reaction (RT-PCR) analysis. Material and Methods Thirty animals (Rattus norvegicus, Albinus Wistar) were divided into three groups after upper incisors extraction at 7, 14, and 28 days. Micro-CT was evaluated based on the morphometric parameters. Subsequently, the histological analyses and immunostaining of osteoprotegerin (OPG), receptor activator of nuclear kappa B ligand (RANKL) and tartrate resistant acid phosphate (TRAP) was performed. In addition, RT-PCR analyses of OPG, RANKL, the runt-related transcription factor 2 (RUNX2), osteocalcin (OC), osteopontin (OPN), osterix (OST) and receptor activator of nuclear kappa B (RANK) were performed to determine the expression of these proteins in the alveolar bone healing. Results Micro-CT: The morphometric parameters of bone volume and trabecular thickness progressively increased over time. Consequently, a gradual decrease in trabecular separation, trabecular space and total bone porosity was observed. Immunohistochemical: There were no differences statistically significant between the positive labeling for OPG, RANKL and TRAP in the different periods. RT-PCR: At 28 days, there was a significant increase in OPG expression, while RANKL expression and the RANKL/OPG ratio both decreased over time. Conclusion Micro-CT showed the newly formed bone had favorable morphometric characteristics of quality and quantity. Beyond the RUNX2, OC, OPN, OST, and RANK proteins expressed in the alveolar bone healing, OPG and RANKL activity showed to be essential for activation of basic multicellular units during the alveolar bone healing.

Daily melatonin administration improves osseointegration in pinealectomized rats

Abstract The hypothesis of this study was that the peri-implant bone healing of the group of pinealectomized rats would differ from the control group. The samples were subjected to immunohistochemical, microtomographic (total porosity and connectivity density), and fluorochrome (mineralized surface) analyses. Objectives The goal of this study was to investigate the cellular changes and bone remodeling dynamics along the bone/implant interface in pinealectomized rats. Material and Methods The total of 18 adult male rats (Rattus norvegicus albinus, Wistar) was divided into three groups (n=6): control (CO), pinealectomized without melatonin (PNX) and pinealectomized with melatonin (PNXm). All animals were submitted to the first surgery (pinealectomy), except the CO group. Thirty days after the pinealectomy without melatonin, the second surgery was conducted, in which all animals received an implant in each tibia (36 titanium implants with surface treatment were installed - Implalife® São Paulo, SP, Brazil). By gavage, the rats of the PNX group received the vehicle solution, and the procedure. Results Immunohistochemical analysis for runt-related transcription factor 2 (RUNX2), alkaline phosphatase (ALP), osteopontin (OP) and osteocalcin (OC) showed that the bone repair process in the PNXm group was similar to that of the CO group, whereas the PNX group showed a delay. The microtomographic parameters of total porosity [Po(tot)] and bone surface (BS) showed no statistically significant differences, whereas for the connective density (Conn.Dn) a statistical difference was found between the CO and PNXm groups. Fluorochrome analysis of the active mineralized surface showed statistically significant difference between the CO and PNX and between the CO and PNXm groups. Conclusion The absence of the pineal gland impaired the bone repair process during osseointegration, however the daily melatonin replacement was able to restore this response.

Association between Facial Type and Mandibular Canal Morphology - Analysis in Digital Panoramic Radiographs

Abstract In this study we investigate the association between facial type and mandibular canal course morphology analysing this in digital panoramic radiographs images. We used 603 digital images from panoramic radiographs. We selected only panoramic radiographs of fully dentate individuals, who had all lower molars bilaterally and with complete root formation. The sample distribution was determined by facial type and sex. The course of the mandibular canal, as seen in the panoramic radiographs, was classified into 3 types, bilaterally. The classification used was: type 1 if the mandibular canal is in contact or is positioned at most 2 mm from the root apex of the three permanent molars; type 2 if the mandibular canal is located halfway between the root apex of the three permanent molars and a half away from the mandibular basis; and type 3 if the mandibular canal is in contact with or approaches, a maximum of 2 mm from the cortical bone of the mandibular basis. For results, the data were analyzed by Chi-square test (p<0.05). Data analysis (Chi-square) showed there were more canals type 2 (p=0.0012) and fewer canals type 1 (p=0.0336) in females than in males, without association with the facial types. In conclusion, the facial type does not associated with the mandibular canal course analyzed.

Resumo Neste estudo investigamos a associação entre o tipo facial e o trajeto do canal mandibular por meio de análises em imagens de radiografia panorâmica digital. Foram utilizadas 603 imagens de radiografias panorâmicas digitais. Foram selecionadas apenas radiografias panorâmicas de indivíduos totalmente dentados, que apresentaram todos os dentes molares inferiores bilateralmente e com completa formação das raízes. A amostra foi determinada pelo tipo facial e pelo sexo. O trajeto do canal mandibular, avaliado nas radiografias panorâmicas, foi classificado em 3 tipos bilateralmente. A classificação usada foi: tipo 1 se o canal mandibular estiver em contato ou posicionado a no máximo 2 mm do ápice radicular dos 3 molares permanentes; tipo 2 se o canal mandibular estiver a meia distância do ápice radicular dos 3 molares permanentes e da base da mandíbula; e tipo 3 se o canal mandibular estiver em contato com ou posicionado a no máximo 2 mm do osso cortical da base da mandíbula. Para os resultados, os dados foram analisados pelo teste qui-quadrado (p<0,05). Os dados analisados (qui-quadrado) mostraram que existem mais canais do tipo 2 (p=0,0012) e menos canais tipo 1 (p=0,0336) em indivíduos femininos do que em masculinos, sem associação com os tipos faciais. Conclui-se que o tipo facial não está associado ao trajeto do canal mandibular.

Analysis of the frontal sinus morphology and the titanium plates shape in skull fracture for human identification / Análisis de la morfología del seno frontal y la forma de la placa de titanio en fractura de cráneo para la identificación humana

Human identification can be performed by several methods, as anatomical structures of the facial skeletal and individuals signals. The aim of this study was to report a case of human identification from the morphological evaluation of the frontal sinus and the presence of titanium plates in skull after examination of Postero Anterior (PA) radiographs ante and postmortem. In 2008 a skull was found on a highway. Later, an alleged victim was found , who disappeared in late 2007. The skull showed postmortem teeth lost, presence of round hole in the right supra-orbital region, consistent with lesion caused by gunshot. It was also noted the presence of a miniplate of bone fixation in the form of inverted "T" in several locations of the nasal bones and bone remodeling signals in the face. PA radiograph of the skull was performed for the purpose of comparison with the X-rays provided by antemortem family. By overlapping radiographic images, there was similarity between the characteristics presented by the skull and found the alleged victim, as the frontal sinus, shape and height of the orbits, and miniplate fixation of bone with the same shape and size, not leaving no doubt that the radiographs belong to the same individual.

La identificación humana puede realizarse por varios métodos, entre ellos a partir de estructuras anatómicas del esqueleto facial y del reconocimiento de señales individuales. El objetivo de este estudio fue reportar un caso de identificación humana mediante la evaluación morfológica del seno frontal y la presencia de placas de titanio en el cráneo después del examen con radiografías posteroanteriores (PA) ante y post mortem. En 2008, se encontró un cráneo en una carretera. Más tarde, se encontró una presunta víctima, que desapareció a finales de 2007. El cráneo mostró dientes perdidos post mortem, la presencia de un orificio redondeado en la región supraorbital derecha, en consonancia con lesiones causadas por arma de fuego. También se observó la presencia de una miniplaca de fijación ósea en forma de "T" invertida en varios lugares de los huesos nasales y señales de remodelación ósea en la cara. La radiografía posteroanterior del cráneo se realizó con el propósito de comparación con los rayos X antemortem proporcionados por la familia. Por superposición de imágenes radiográficas, hubo similitud entre las características que presentó el cráneo y las de la presunta víctima, ya que el seno frontal, la forma y la altura de las órbitas, y la fijación de la miniplaca de hueso presentaron la misma forma y tamaño, no dejando ninguna duda de que las radiografías pertenecían a la misma persona.

Tooth Loss Related to Root Perforation: Legal Approach in Endodontic Practice / Perdida Dentaria Relacionada con una Perforación Radicular: Una Visión Legal en la Práctica Endodóntica

Most of the techniques used in endodontic treatment are limited to the internal space to the tooth, avoiding reaching the periapical region. However, some accidents can happen, such as fracture of endodontic instruments, perforation, leakage of material, tooth fracture among others, depending on the complexityof each case. The aim of this study was to report a case involving a tooth loss caused by root perforation. In this case, the patient filed a lawsuit against the former professional who had performed endodontic treatment requiring compensation for moral and material damages. In conclusion, the practice endodontic the clarification of the risks is crucial, considering the particularities of each case. Thus, it is suggested that the verbal and written information should be offered to patients.

La mayoría de las técnicas usadas en el tratamiento de endodoncia son limitadas hacia la cavidad dentinaria pulpar coronal y el canal radicular, evitándose alcanzar la región periapical alveolar. Sin embargo, algunos accidentes pueden ocurrir, tales como: fracturas de instrumentos de endodoncia, perforaciones radiculares, extravasación del material de obturación y fracturas dentarias entre otros. Cada uno involucra una respectiva complejidad. El objetivo de esta publicación fue reportar un caso donde ocurrió la pérdida de un diente permanente causado por una perforación radicular. En este caso la paciente presentó una demanda contra el profesional quién realizó el tratamiento de endodoncia, solicitando una compensación por daños morales y materiales. Se concluye que en la práctica de endodoncia, la especificación de los riesgos es crucial, considerándose las particularidades de cada caso. Así, se sugiere que una buena información verbal y escrita deberá ser proporcionada al paciente.

Bone Substitutes used in Dentistry / Sustitutos Óseos Utilizados en Odontología

Repair of bone defects resulting from trauma, tumor resections and infections is a medical and dental problem that needs a practical and low cost solution. To facilitate the repair several grafts or bone substitutes may be applied inside the defects. Biomaterials allow treatment, increase or replacement of any tissue, organ or function of the body. The aim of this study was to approach the advantages, disadvantages and main applications of bone substitutes used in reconstruction searched in dental practice. The manuscripts used in this literature review were searched in Medline (PubMed) and Scopus databases and based on manuscripts published from 1991 to 2012. After reading the titles and abstracts of the manuscripts, studies were selected because of their correlations with the aim of the current study. Bone tissue engineering has emerged as a new area of regenerative medicine and biomaterials and has an essential function concerning osteoconductive scaffold, osteogenic growth factors, and osteogenic cells. Based on literature available, a combination of advantageous properties of natural resorbable polymers and bioactive material in nanoscale appears to be more relevant for use in bone defects.

La reparación de defectos óseos que resultan de traumas, resección de tumores e infecciones son un problema médico y dental que necesitan una solución práctica y de bajo costo. Para facilitar la reparación, diversos injertos o sustitutos óseos pueden ser aplicados en el interior de los defectos. Los biomateriales permiten tratar, aumentar o sustituir algún tejido, órgano o función del cuerpo. El objetivo de este estudio fue acercarse a las ventajas, desventajas y principales aplicaciones de los sustitutos óseos utilizados para la reconstrucción en la práctica dental. Los manuscritos utilizados en esta revisión sistemática de la literatura se realizaron mediante la búsquedas en Medline (PubMed) y bases de datos Scopus, basada en manuscritos aparecidas entre 1991 y 2012. Después de leer los títulos y resúmenes de los manuscritos, los estudios fueron seleccionados debido a su correlación con el objetivo del presente estudio. Ingeniería de tejido óseo se ha convertido en una nueva área de la medicina regenerativa y biomateriales y tiene una función esencial en relación osteoconductivo andamio, factores de crecimiento osteogénicos, y las células osteogénicas. Basado en la literatura disponible, una combinación de propiedades ventajosas de polímeros reabsorbibles naturales y el material bioactivo en nanoescala que parece ser más relevante para su uso en defectos óseos.

Computer graphics applied to anatomy: a study of two Bio-CAD modeling methods on finite element analysis of human edentulous hemi-mandible / Computación gráfica aplicada a la anatomía: un estudio de dos métodos de modelización Bio-CAD sobre el análisis de elementos finitos de hemimandíbulas edéntulas humanas

Modeling is a step to perform a finite element analysis. Different methods of model construction are reported in literature, as the Bio-CAD modeling. The purpose of this study was to perform a model evaluation and application using two methods of Bio-CAD modeling from human edentulous hemi-mandible on the finite element analysis. From CT scans of dried human skull was reconstructed a stereolithographic model. Two methods of modeling were performed: STL conversion approach (Model 1) associated to STL simplification and reverse engineering approach (Model 2). For finite element analysis was used the action of lateral pterygoid muscle as loading condition to assess total displacement (D), equivalent von-Mises stress (VM) and maximum principal stress (MP). Two models presented differences on the geometry regarding surface number (1834 (model 1); 282 (model 2)). Were observed differences in finite element mesh regarding element number (30428 nodes/16683 elements (model 1); 15801 nodes/8410 elements (model 2). D, VM and MP stress areas presented similar distribution in two models. The values were different regarding maximum and minimum values of D (ranging 0­0.511 mm (model 1) and 0­0.544 mm (model 2), VM stress (6.36E-04­11.4 MPa (model 1) and 2.15E-04­14.7 MPa (model 2) and MP stress (-1.43­9.14 MPa (model 1) and -1.2­11.6 MPa (model 2). From two methods of Bio-CAD modeling, the reverse engineering presented better anatomical representation compared to the STL conversion approach. The models presented differences in the finite element mesh, total displacement and stress distribution.

El modelado es un paso para llevar a cabo un análisis de elementos finitos. Entre los diferentes métodos de construcción del modelo que se presentan en la literatura, está el modelado Bio-CAD. El propósito de este estudio fue realizar una evaluación del modelo y aplicación utilizando dos métodos de modelado de Bio-CAD desde la hemimandíbula humana edéntula en el análisis de elementos finitos. Desde tomografías computarizadas de cráneos humanos secos, fue reconstruido un modelo de estereolitografía. Se realizaron dos métodos de modelización: enfoque conversión STL (Modelo 1) asociado a simplificación STL y enfoque de ingeniería inversa (Modelo 2). Para el análisis de elementos finitos se utilizó la acción del músculo pterigoideo lateral como condición de carga para evaluar desplazamiento total (D), lo que equivale tensión de von Mises (VM) y la tensión principal máxima (MP). Los dos modelos presentan diferencias en la geometría de la superficie en relación con el número (1834 (modelo 1), 282 (modelo 2)). Se observaron diferencias en la malla de elementos finitos con respecto a número de elemento (30428 nodos/16683 elementos (modelo 1) y 15.801 nodos/8410 elementos (modelo 2)). La D, VM y áreas de tensión MP presentan distribución similar en ambos modelos. Los valores fueron diferentes respecto a los valores máximo y mínimo de D (desde 0 hasta 0,511 mm (modelo 1) y 0 a 0,544 mm (modelo 2), tensión VM (6,36E-04 - 11,4 MPa (modelo 1) y 2,15e-04 - 14,7 MPa (modelo 2) y tensiones MP (-1,43 a 9,14 MPa (modelo 1) y -1,2 a 11,6 MPa (modelo 2)) a partir de dos métodos de modelado de Bio-CAD. La ingeniería inversa presenta una mejor representación anatómica en comparación con el enfoque de conversión STL. Los modelos presentan diferencias en la malla de elementos finitos, el desplazamiento total y la distribución de la tensión.

Relations between the mandibular canal and I, II and III Angle classes in panoramic radiographs / Relaciones entre el canal mandibular y clases I, II y III de Angle en radiografías panorámicas

To prevent injury to the inferior alveolar nerve during dental procedures, knowledge of its anatomical location and course of the mandibular canal is imperative. The aim of this study was evaluate the location on panoramic radiographs of the mandibular canal in relation to the apices of the permanent mandibular molars and base mandible, and relate the type of mandibular canal with Angle classes I, II and III. We evaluated 748 panoramic radiographs distributed according to sex and occlusal class (Angle I, II and III) of fully dentate individuals, 18­51 age group. The radiographs were divided according to Angle classes based on cephalometric tracing, clinical data from the medical records of each individual and the analysis of of the maxillar and mandibular dental arches models. The same individuals had the mandibular canal bilaterally assessed, and classified according to their location relative to the root apices of the mandibular molars and mandible base. Measurements of the distance from the mandibular canal to the apices of the teeth and mandible base were made on the Software ImageLab2000®. The intra-observer reproducibility of measurements on radiographs was assessed using the coefficient of variation (p<0.0001). Data were submitted to Kruskal-Wallis test, on software BioEstat 5.0. There were statistically significant differences (Kruskal-Wallis test, p <0.0001) between the occlusal classes, with the type of mandibular canal. A larger number of canals types 2 and 3 in class III individuals than in others. In conclusion, the location of the mandibular canal presents morphological changes in relation to the apices of the permanent molars, and the mandibular base according to the Angle classes I, II and III.

Para evitar lesiones del nervio alveolar inferior durante los procedimientos odontológicos, el conocimiento de la localización anatómica y curso del canal mandibular (CM) es imprescindible. El objetivo fue evaluar la localización del CM sobre radiografías panorámicas en relación con los ápices de los molares mandibulares permanentes y la base mandibular, relacionando el tipo de CM con las clases I, II y III de Angle. Se evaluaron 748 radiografías panorámicas distribuidas según sexo y clase oclusal (I, II y III de Angle) en individuos totalmente dentados (edad entre 18-51 años). Las radiografías fueron divididas de acuerdo a las clases de Angle según su trazado cefalométrico, datos clínicos de los registros médicos de cada individuo y el análisis de modelos de sus arcos dentarios mandibulares y maxilares. En los individuos se evaluó el CM bilateralmente y se clasificó de acuerdo a su ubicación en relación con los ápices radiculares de los molares mandibulares y base mandibular. Las mediciones de distancia desde el CM a los ápices radiculares y base mandibular se hicieron con el programa ImageLab2000®. Se evaluó la reproducibilidad intra-observador de las mediciones en las radiografías usando el coeficiente de variación (p<0,0001). Los datos fueron sometidos a la prueba de Kruskal ­Wallis con el programa BioEstat 5.0. Se observaron diferencias estadísticamente significativas (prueba de Kruskal-Wallis, p<0,0001) entre las clases oclusales y el tipo de CM. Hubo mayor número de canales tipos 2 y 3 en los individuos clase III. La ubicación del canal mandibular presenta cambios morfológicos en relación con los ápices de molares permanentes y la base mandibular de acuerdo a las clases I, II y III de Angle.

The application of finite element analysis in the skull biomechanics and dentistry.

Empirical concepts describe the direction of the masticatory stress dissipation in the skull. The scientific evidence of the trajectories and the magnitude of stress dissipation can help in the diagnosis of the masticatory alterations and the planning of oral rehabilitation in the different areas of Dentistry. The Finite Element Analysis (FEA) is a tool that may reproduce complex structures with irregular geometries of natural and artificial tissues of the human body because it uses mathematical functions that enable the understanding of the craniofacial biomechanics. The aim of this study was to review the literature on the advantages and limitations of FEA in the skull biomechanics and Dentistry study. The keywords of the selected original research articles were: Finite element analysis, biomechanics, skull, Dentistry, teeth, and implant. The literature review was performed in the databases, PUBMED, MEDLINE and SCOPUS. The selected books and articles were between the years 1928 and 2010. The FEA is an assessment tool whose application in different areas of the Dentistry has gradually increased over the past 10 years, but its application in the analysis of the skull biomechanics is scarce. The main advantages of the FEA are the realistic mode of approach and the possibility of results being based on analysis of only one model. On the other hand, the main limitation of the FEA studies is the lack of anatomical details in the modeling phase of the craniofacial structures and the lack of information about the material properties.

Biomechanics of the human canine pillar based on its geometry using finite element analysis / Biomecánica del pilar canino en el cráneo humano basada en la geometría utilizando análisis de elementos finitos

This study evaluated the stress distribution based on the canine pillar geometry in human skull, using a finite element analysis. Computed tomography of human skull was used to build a finite element model, which was composed by all bony structures of canine pillar: canine eminence, canine fossa, frontal process of maxilla, glabellum and superciliary arch. A support on the bite contact of maxillary canine tooth and a resultant force of the masticatory muscles was applied in the simulation. Equivalent Von-mises and maximum principal stresses were analyzed along the structures that compose the canine pillar geometry. Von-mises stress presented high stress concentrated at the canine fossa and frontal process of maxilla. Maximum principal stress showed compression areas at the canine fossa and part of frontal process and tensile stress at canine eminence and part of the frontal process. In conclusion, the different stress areas means different force concentrations transmitted along the canine pillar geometry during a peak canine bite.

Este estudio evaluó la distribución de la tensión sobre la geometría del pilar canino en el cráneo humano, utilizando análisis de elementos finitos. Se usó la tomografía computarizada de cráneo humano para construir un modelo de elementos finitos compuesto por todas las estructuras óseas del pilar canino: eminencia canina, fosa canina, proceso frontal del maxilar, glabela y arco superciliar. Se aplicó en la simulación un soporte ubicado sobre el contacto de mordida del diente canino maxilar y una fuerza resultante de los músculos de la masticación. Tensiones Equivalentes de Von-Mises y tensiones principales máximas fueron analizadas a lo largo de las estructuras que componen la geometría de pilar canino. La tensión de Von-Mises fue alta y concentrada en la fosa canina y proceso frontal del maxilar. La tensión principal máxima mostró áreas de compresión en la fosa canina y parte del proceso frontal y la tensión de tracción en la eminencia canina y parte del proceso frontal. Las diferentes áreas de tensión significan diferentes concentraciones de tensiones transmitida a lo largo de la geometría del pilar canino durante una mordedura canina máxima.

Stress distribution in human zygomatic pillar using three-dimensional finite element analysis / Distribución de la tensión en el pilar cigomático humano usando análisis de elementos finitos tridimensional

This paper aimed to analyze stress distribution in human zygomatic pillar during masseter muscle contraction using three-dimensional finite element analysis. A three-dimensional model and hemi facial skull were produced based on CT-scan data. An adult male skull with structural anatomy integrity was used as model. Muscles forces were applied at origin of elevator muscles and supports was applied at the occlusal surfaces at first and second molars to simulate a masticatory load and stimulate the zygomatic pillar. Supports were applied to the occlusal contacts. Symmetry conditions were placed at the mid-sagittal plane. For the top and back cutting plane, constraints were used. Equivalent Von-Mises Stress and Maximum Principal Stress analysis were performed from the stress fields along the zygomatic pillar. It was represented by stress concentration at the alveolar process, zygomatic bone, frontal and temporal process of zygomatic bone and superciliary arch. Stress line indicates distribution of stress from maxilla toward the frontal and temporal bone. The stresses occurred due to resultant occlusal forces is mainly supported by the zygomatic bone, non-uniformly distributed and predominantly through the zygomatic pillar. This study contributed to better understanding of stress distribution in zygomatic pillar to understand the influence of chewing on zygomatic pillar morphology and also be useful for clinical practice.

El objetivo de este artículo fue analizar la distribución de la tensión en el pilar cigomático humano durante la contracción del músculo masetero utilizando análisis de elementos finitos tridimensionales. Un modelo de tres dimensiones de dientes del hemicráneo facial fueron producidos sobre la base de datos de CT-scan. Se utilizó como modelo un cráneo adulto de sexo masculino con la integridad de la anatomía estructural. Fuerzas musculares se aplicaron en el origen de los ascensores de los músculos de la mandíbula y soportes se aplicaron a la superficie oclusal del primer y segundo molar para simular una carga masticatoria y estimular el pilar cigomático. Condiciones de simetría se colocaron en el plano mediano. Se utilizaron restricciones en los planos superior y posterior. El análisis de las tensiones equivalentes von-Mises y máximo director se realizó a través del campo de esfuerzos a lo largo del pilar cigomático. Fue representada la concentración de esfuerzos en el proceso alveolar, hueso cigomático, proceso frontal y temporal del hueso cigomático y el arco superciliar. La línea de tensión indica la distribución de la tensión del maxilar hacia el hueso frontal y temporal. Las tensiones se produjeron debido a las fuerzas oclusales resultantes, que se apoyan principalmente por el hueso cigomático, distribuidas de manera no uniforme y sobre todo a través del pilar cigomático. Este estudio ha contribuido a una mejor comprensión de la distribución de la tensión en el pilar cigomático para entender la influencia de la masticación sobre la morfología de este pilar y ser de utilidad en la práctica clínica.

Orthodontic Extrusion of the Upper Central Incisor: A Rare Case of Pulp Mummification / Extrusión Ortodóncica del Incisivo Central Superior: un Caso Raro de Momificación Pulpar

Due to its anatomical positioning, the central upper incisors are the most affected teeth when related to trauma injuries in the craniofacial region, among with nose traumas. In childhood, traumatic injury is most often caused by bicycle accidents, sports, recreational activities or falls. The aim of this report is to describe a treatment for intrusion of the left maxillary central incisor and the subsequent complications in an 8-year-old boy. Also, the report emphasizes the importance of careful long-term follow-up monitoring intruded permanent teeth. Pulp tissue, as other tissues in the human body, tends to change with traumas. Some of those changes are natural while others occur as result of injuries to the dentin-pulp complex such as caries lesions, periodontal disease, calcifications, as in the present report, or restorative dental procedures. Normally conducted endodontic treatment must take place to obtain maximal results, but only after the re-stabilization of the tooth.

Debido a su localización anatómica, los incisivos centrales superiores son los dientes más afectados cuando se refieren a las lesiones traumáticas de la región craneofacial, entre los traumas nasales. En la infancia, lesión traumática suele ser ocasionado por accidentes de bicicleta, deportes, actividades recreativas o caídas. El objetivo de este artículo es describir un tratamiento para la intrusión del incisivo central superior izquierdo y las complicaciones posteriores en un niño de 8 años de edad. Asimismo, el informe hace hincapié en la importancia de cuidado a largo plazo con un seguimiento intrusión dientes permanentes. Tejido de la pulpa, como otros tejidos en el cuerpo humano, tiende a cambiar con traumas. Algunos de estos cambios son naturales, mientras que otros se producen como consecuencia de las lesiones del complejo dentina-pulpa, como las lesiones de caries, enfermedad periodontal, calcificaciones, como en el presente informe, restauración o intervención dental. Tratamiento endodóntico a cabo normalmente deben tener lugar para obtener los máximos resultados, pero sólo después de la re-estabilización del diente.

Emissary foramens of the human skull: anatomical characteristics and its relations with clinical neurosurgery / Forámenes emisarios del cráneo humano: características anatómicas y sus relaciones con la neurocirugía clínica

The recognition of emissary foramens is important not only for understanding the regional neurovascular anatomy, but also to distinguish normal from potentially abnormal structures. Thus, the aim of this study was to review the literature on anatomical and clinical aspects of the mastoid, parietal and sphenoid emissary foramens. It was found that the emissary foramen presents importance in clinical practice because it acts as a route of spread of extracranial infection to the intracranial structures and also possible complications in neurosurgery, due to its influence in the performance of techniques such as radiofrequency rhizotomy for treatment of trigeminal neuralgia. The anatomical knowledge of the emissary foramens is important due to variability in their incidence in the human skull and its relation to the dura mater sinuses.

El reconocimiento de forámenes emisarios es importante no sólo para la comprensión de la anatomía neurovascular regional, sino también para distinguir lo normal a partir de estructuras potencialmente anormales. El objetivo de este estudio fue revisar la literatura sobre los aspectos anatómicos y clínicos del proceso mastoide, huesos parietal y esfenoides y forámenes emisarios. El foramen emisario adquiere importancia en la práctica clínica debido a que actúa como una vía de propagación de la infección extracraneal a las estructuras intracraneales, y también con las posibles complicaciones en neurocirugía, debido a su influencia en el desarrollo de técnicas como rizotomía por radiofrecuencia en el tratamiento de neuralgia del trigémino. El conocimiento anatómico de los forámenes emisarios es importante debido a la variabilidad en su incidencia en el cráneo humano y su relación con los senos de la duramadre.

Incidence of the mandibular accessory foramina in Brazilian population

In adults, the mandibular accessory foramina are variables and are located on the medial surface of the mandible in positions above or below of the mandibular foramen. The aim of this study was to evaluate the incidence of the mandibular accessory foramina in Brazilians human mandibles and discuss the clinical aspects related to the presence of these foramina. Were evaluated 222 mandibles, adults, irrespective of gender. Was observed that 27.93% and 43.24% of the mandibles presented at least one mandibular accessory foramina located on the medial surface in position below and above, respectively, of the mandibular foramen. Unilaterally, the mandibular accessory foramina were observed below and above of the mandibular foramen in 22.07% and 25.22%, of the mandibles, respectively, and 5.85% and 18.02% bilaterally, respectively. This study demonstrated that the incidence of mandibular accessory foramen in the Brazilian population is significant and should be considered in the planning and execution of procedures in several areas of dental clinical practice in order to avoid complications.

Incidence of retromolar foramen in human mandibles: ethnic and clinical aspects / Incidencia del foramen retromolar en mandibulas humanas: aspectos étnicos y clínicos

The retromolar foramen allows the passage of the neurovascular bundles that contribute to nutrition and innervation of the pulp and periodontium of the lower teeth. Knowledge of this anatomical variation may prevent complications in the anesthesia and surgical procedures in this area and serve as an anatomical landmark for ethnic identification. The aim of this study was to evaluate the impact of the retromolar foramen in human mandibles of adult Brazilians and discuss the clinical and ethnic related to the presence of this foramen. Were evaluated 222 human mandibles, dry, adults, Brazilians, independent of gender. The evaluation was performed by two examiners who standardized search from a previous anatomical study. The mandibles were analyzed: the presence of the retromolar foramen (bilateral or unilateral), the presence of the foramen on right and left sides, and the number of foramens present on each side. It was found that 59 had at least one mandible retromolar foramens resulting in an incidence of 26.58 percent The retromolar foramen was present unilaterally in 41 mandibles and 18 bilaterally, with incidences of 18.47 percent and 12.16 percent respectively. On the right side, the retromolar foramen was present in incidences of 16.22 percent and 18.92 percent respectively. The analysis of the right side of the mandibles revealed that 47.46 percent, 21.21 percent and 3.03 percent had one, two and three foramens, respectively. The left side showed 55.93 percent, 16.22 percent and 8.11 percent of the 222 mandibles with one, two and three retromolar foramens, respectively. The incidence of retromolar foramen in the Brazilian population is significant and should be considered in the planning and execution of procedures in several areas of clinical practice dentistry in order to avoid complications. Moreover, it was found that the incidence of retromolar foramen contributes to differentiation of ethnic groups in the area of forensic anthropology...

El foramen retromolar permite el paso de los haces neurovasculares que contribuyen a la nutrición y inervación de la pulpa y periodonto de los dientes mandibulares. Conocer sus variaciones anatómicas pueden prevenir complicaciones de la anestesia y procedimientos quirúrgicos, y servir de punto de referencia anatómico para la identificación étnica. El objetivo de este estudio fue evaluar el impacto del foramen retromolar en mandíbulas humanas de brasileños adultos y discutir la relación clínica y étnica de la presencia de este foramen. Se evaluaron 222 mandíbulas humanas secas de adultos brasileños, independiente del sexo. La evaluación fue efectuada por dos examinadores que realizaron búsquedas estándar de un estudio anatómico anterior. En las mandíbulas se examinaron: la presencia del foramen retromolar (bilateral o unilateral), lados (derecho e izquierdo), y el número de forámenes presentes en cada lado. En 59 mandíbulas se observó al menos un foramen retromolar, una incidencia del 26,58 por ciento. El foramen retromolar estuvo presente de manera unilateral en 41 mandíbulas, bilateralmente en 18, con una incidencia del 18,47 por ciento y 12,16 por ciento, respectivamente. En el lado derecho, el foramen retromolar estuvo presente en el 16,22 por ciento y 18,92 por ciento respectivamente. El análisis de la parte derecha de la mandíbula reveló que 47,46 por ciento, 21,21 por ciento y 3,03 por ciento tuvo uno, dos y tres forámenes, respectivamente. El lado izquierdo mostró 55,93 por ciento, 16,22 por ciento y 8,11 por ciento con uno, dos y tres forámenes retromolares, respectivamente. La incidencia del foramen retromolar en la población brasileña es significativo y se debe considerar en la planificación y ejecución de los procedimientos en varias áreas de la odontología clínica con el fin de evitar complicaciones. Por otra parte, se constató que la incidencia del foramen retromolar contribuye a la diferenciación de los grupos étnicos en el área de la...

Use of homologous bone grafts in maxillary sinus lifting / Uso de injertos de hueso homólogo en la elevación del seno maxilar

Homologous bone has been considered a viable alternative in bone reconstruction in the posterior maxillary area to perform surgeries for the maxillary sinus lifting. The aim of this study was to perform a literature review about the advantages and risks inherent in the use of homologous bone graft coming from the tissue bank to perform the surgery for maxillary sinus lifting. A literature review was conducted on MEDLINE (PubMed), Scielo, Scopus and Lilacs, and based on manuscripts and books published from 1980 to 2010. After reading the titles and abstracts of the manuscripts, 69 studies were selected because of their correlations with the aim of the current study. The use of homologous grafts from bone banks showed greater osteogenic potential and a slow remodeling least compared to other grafts to increase the volume of the posterior bone of the maxilla in surgery for maxillary sinus lifting.

De hueso homólogo se ha considerado una alternativa viable en la reconstrucción ósea en la zona posterior del maxilar para cirugías de la elevación del seno maxilar. El objetivo de este estudio fue el desempeño de una revisión de la literatura sobre las ventajas y riesgos inherentes en el uso de injerto de hueso homólogo proveniente del banco de tejidos para la cirugía de elevación del seno maxilar. Una revisión de la literatura se hizo en MEDLINE (PubMed), Scielo, Scopus y Lilacs, y en base a manuscritos y libros publicados desde 1980 hasta 2010. Después de leer los títulos y resúmenes de los manuscritos, 69 estudios fueron seleccionados debido a su correlación con el objetivo de este estudio. El uso de injertos homólogos de los bancos de hueso mostró un mayor potencial osteogénico y una remodelación lento por lo menos en comparación con otros injertos para aumentar el volumen del hueso posterior del maxilar superior en la cirugía de elevación del seno maxilar.

Short implants in oral rehabilitation

Introduction and objective: The placement of short dental implants is used as an alternative treatment modality to bone grafting procedures. The aim of this study was to discuss, through a literature review, the features, indications and biomechanical aspects of short implants, as well as to report the clinical factors that influence on their indication. Literature review and conclusion: It was found that short implants osseointegration can be compromised by risk factors that must be controlled to achieve treatment success. In conclusion, the main indication of short implants is to avoid an invasive surgery at atrophic areas of maxilla and mandible. Furthermore, implant design associated with surface treatment are factors that compensate its short length.